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Choi SH, Cho HB, Choi JH, Kim HJ, Jang HJ, Cho SH, Maeng EC, Park HI, Ryu KS, Park KH, Park KS*. Nano-chemical priming strategy to enhance TGF-β resistance and anti-tumor activity of natural killer cells. Journal of Controlled Release. 2024 Mar.
(2024 IF: 10.8)


Choi JH, Park JD, Choi SH, Ko ES, Jang HJ, Park KS* ELK3-ID4 axis governs the metastatic features of triple negative breast cancer. Oncology Research 2023 Nov, 32(1), 127-138. (2023 IF: 4.938)

Park JD, Jang HJ, Choi SH, Jo GH, Choi JH, Hwang S, Park W, Park KS*. The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics. Cell Death Discov. 2023 Jul 8;9(1):237.

(2023 IF: 7.113)

Ko ES, Choi SH , Lee M, Park KS*. 25KDa branched polyethylenimine increases interferon-γ production in natural killer cells via improving translation efficiency. Cell Communication and Signaling. 2023 May 21:107 (2023 IF: 7.54)


Jung HY, Lee DK, Lee M, Choi SH, Park JD, Ko ES, Lee J, Park KS*, Jung HY. ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer. Oncoimmunology. 2023 Mar 17;12(1):2190671. (2023 IF: 7.723)


Choi SH, Kim HJ, Park JD,  Ko ES, Lee M, Lee DK, Choi JH, Jang HJ, Kim I, Jung HY, Park KH, Park KS*. Chemical priming of natural killer cells with branched polyethylenimine for cancer immunotherapy. J Immunother Cancer. Aug;10(8):e004964 (2022) (2022 IF: 12.469) *Co-coresponding author

Park JD, Kim KS, Choi SH, Jo GH, Choi JH, Park SW, Ko ES, Lee M, Lee DK, Jang HJ, Hwang S, Jung HY, Park KS*. ELK3 modulates the antitumor efficacy of natural killer cells against triple negative breast cancer by regulating mitochondrial dynamics. J Immunother Cancer. Jul;10(7):e004825 (2022) (2022 IF: 12.469)

Kim P, Park J, Lee DJ, Mizuno S, Shinohara M, Hong CP, Jeong Y, Yun R, Park H, Park S, Yang KM, Lee MJ, Jang SP, Kim HY, Lee SJ, Song SU, Park KS, Tanaka M, Ohshima H, Cho JW, Sugiyama F, Takahashi S, Jung HS, Kim SJ. Mast4 determines the cell fate of MSCs for bone and cartilage development. Nat Commun. Jul 8;13(1):3960 (2022) (2022 IF: 17.694)

Lee M, Cho HJ, Park KS*, Jung HY. ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes. Int J Mol Sci. Mar 28;23(7):3709 (2022) (2022 IF: 6.208) *Co-coresponding author

Pang K, Lee J, Kim J, Park J, Park Y, Hong E, An H, Ooshima A, Son M, Park KS, Cho JH, Lee C, Song YS, Yang KM, Kim SJ. Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells. Cell Death Dis. Feb 22;13(2):169 (2022) (2022 IF: 9.685)


Jung D, Baek YS, Lee IJ, Kim KY, Jang H, Hwang S, Jung J, Moon YW, Park KS, Choi YS, An HJ. Ex vivo expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells through different receptor-ligand interactions. J Exp Clin Cancer Res. Oct 23;40(1):333 (2021) (2021 IF: 11.161)

Choi SH, Jung D, Kim KY, An HJ, Park KS*. Combined use of cisplatin plus natural killer cells overcomes immunoresistance of chemoresistant ovarian cancer cells. Biochem Biophys Res Commun. 563:40-46 (2021) (2020 IF: 3.575)

Lee AR, Park JH, Shim SH, Hong K, La H, Park KS*, Lee DR*.Genome stabilization by RAD51 stimulatory compound 1 enhances efficiency of somatic cell nuclear transfer-mediated reprogramming and full-term development of cloned mouse embryos. Cell Proliferation. 54(7):e13059 (2021) (2020 IF: 6.831)

Park S, Arai Y, Bello A, Park H, Kim D, Park KS, Lee SH. SPRY4 acts as an indicator of osteoarthritis severity and regulates chondrocyte hypertrophy and ECM protease expression. NPJ Regen Med. 6:56 (2021) (2020 IF: 8.60)

Lee GH, An HJ, Kim TH, Kim G, Park KS, Park H, Lee TH, Kwon AY. Clinical Impact of Natural Killer Group 2D Receptor Expression and That of Its Ligand in Ovarian Carcinomas: A Retrospective Study. Yonsei Med J. Apr;62(4):288-297 (2021) (2021 IF: 2.86)

An H, Heo JS, Kim P, Lian Z, Lee S, Park J, Hong E, Pang K, Park Y, Ooshima A, Lee J, Son M, Park H, Wu Z, Park KS, Kim SJ*, Yang KM*. Tetraarsenic hexooxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GADME in triple-negative breast cancer cells. Cell Death & Dis. 12(2):159 (2021) (2020 IF: 8.469)


Kim KS, Han JH ,  Choi SH, Jung HY, Park JD, An HJ, Kim SE, Kim DH, Doh J, Han DK, Kim IH,  Park W*, Park KS*. Cationic nanoparticle-mediated activation of natural killer cells for effective cancer immunotherapy. ACS appl mater & interfaces. 12(51):56731-56740 (2020) (2020 IF: 9.229)

Kim HK†, Park JD†, Choi SH, Shin DJ, Hwang S, Jung HY*, Park KS*. Functional Link between miR-200a and ELK3 Regulates the Metastatic Nature of Breast Cancer. Cancers (2020) (2020 IF: 6.639)


Park Y, Pang K, Park J, Hong E, Lee J, Ooshima A, Kim HS, Cho JH, Han Y, Lee C, Song YS, Park KS, Yang KM, Kim SJ. Destabilization of TRAF6 by DRAK1 suppresses tumor growth and metastasis in cervical cancer cells. Cancer Research (2020)   (2020 IF: 12.701)


Park JH, Park KS*. SMAD3 promotes ELK3 expression following transforming growth factor beta-mediated stimulation of MDA-MB231 cells. Oncology Letters (2020) (2020 IF: 2.967)



Pang K, Park J, Ahn SG, Lee J, Park Y, Ooshima A, Mizuno S, Yamashita S, Park KS, Lee SY, Jeong J, Ushihima T, Yang KM, Kim SJ. RNF208, an estrogen-inducible E3 ligase, targets soluble vimentin to suppress metastasis in triple negative breast cancers. Nature Communication (2019) (2020 IF: 14.919)


Cho HJ, Oh N, Park JH, Kim KS, Kim HK, Lee E, Hwang SH, Kim SJ, Park KS*. ZEB1 collaborates with ELK3 to repress E-cadherin expression in triple negative breast cancer cells. Molecular Cancer Research (2019) (2020 IF: 5.852)


Kim KS, Han JH, Park JH, Kim HK, Choi SH, Kim GR, Song H, An HJ, Han DK*, Park W*, Park KS*. Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer cell therapeutics. Biomaterials (2019) (2020 IF: 12.479)


Choi YH, Lim EH, Kim SW, Moon YW, Park KS, An HJ. IL-27 enhances IL-15/IL-18 mediated activation of human natural killer cells. J Immuno Therapy of Cancer (2019) (2020 IF: 13.751)


Park S, Arai Y, Kim BJ, Bello A, Ashraf, S, Park H, Park KS*, Lee SH*. Suppression of Spry4 promotes osteogenic differentiation and bone formation of mesenchymal stem cell. Tissue Engineering (2019) (2020 IF: 3.845)


Kim KS, Park JI, Oh N, Cho HJ, Park JH, Park KS*. ELK3 expressed in lymphatic endothelial cells promotes breast cancer progression and metastasis through exosomal miRNAs. Scientific Reports (2019) (2020 IF: 4.379)


Lee JY, Lee SH, Kim KS, Park KH, Park KS*. Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis. Stem Cell Research & Therapy (2019) (2020 IF: 6.832)



Kim KS, Kim J, Oh N, Kim MY, Park KS*. ELK3-GATA3 axis modulates MDA-MB231 metastasis by regulating cell to cell adhesion-related genes. Biochem. Biophys. Res. Commun. (2018) (2020 IF: 3.575)


Park JI, Kim KS, Kong SY, Park KS*. Novel function of E26 transformation-specific domain-containing protein ELK3 in lymphatic endothelial cells. Oncology Letters (2018) (2020 IF: 2.967)


Park TH, Cho HJ, Lee JW, Kim CW, Chong Y, Chang CH, Park KS*. Could -79°C spray-type cryotherapy be an effective monotherapy for the treatment of keloid? International J of Molecular Sciences (2017) (2020 IF: 4.556)


Cho EH, Yoon S, Park KS, Kim KP. The homologous recombination machinery orchestrates post-replication DNA repair during self-renewal of mouse embryonic stem cells. Scientific Reports (2017) (2020 IF: 4.379)


Kim I, Kim KS, Kown OS, Park KS*. Ell3 stimulates 5-FU resistance in a breast cancer cell line. Oncology Letters (2017) (2020 IF: 2.967)


Lee JY, Park Y, Oh N, Kwack K, Park KS*. A transcriptional complex composed of ER(a), GATA3, FOXA1 and Ell3 regulates IL-20 expression in breast cancer cells. Oncotarget (2017)


Oh N, Park JI, Park JH, Kim KS, Lee DR, Park KS*. The role of ELK3 to regulate peritumoral lymphangiogenesis and VEGF-C production in triple negative breast cancer cells. Biochem Biophys Res Commun. 484(4):896-902 (2017) (2020 IF: 3.575)


Kim KH, Park JH, Kim EY, Ko JJ, Park KS*, Lee KA*. The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes. Scientific Reports. 6:34110 (2016) (2020 IF: 4.379)


Kong SY, Kim KS, Kim J, Kim MK, Lee KH, Lee JY, Oh N, Park JI, Heo SH, Shim SH, Lee DR, Kim KP, Park KS*. The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo. Oncotarget. 7(40):65137-65146 (2016)


Park JH, Kim KP, Ko JJ, Park KS*. PI3K/Akt/mTOR activation by suppression of ELK3 mediates chemosensitivity of MDA-MB-231 cells to doxorubicin by inhibiting autophagy. Biochem. Biophys. Res. Commun. 477(2):277-282 (2016) (2020 IF: 3.575)


Ahn HJ, Kim KS, Shin KW, Lim KH, Kim JO, Lee JY, Kim J, Park JH, Yang KM, Baek KH, Ko JJ, Park KS*. Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteosomal degradation pathways in breast cancer cells. Oncotarget. 6(42): 44523-44537 (2015)


Lee JY, Lee SH, Heo SH, Kim KS, Kim C, Kim DK, Ko JJ, Park KS*. Novel function of lysine methyltransferase G9a in the regulation of Sox2 protein stability. PLoS ONE. 10(10): e0141118 (2015) (2020 IF: 3.240)


Heo SH, Lee JY, Yang KM, Park KS*. ELK3 expression correlates with cell migration, invasion and membrane type 1-matrix metalloproteinase expression in MDA-MB-231 breast cancer cells. Gene Expression. 16(4):197-203 (2015) (2020 IF: 5.057)


Park JI, Kim KS, Kong SY, Park KS*. Novel function of ELK3 in the lymphatic endothelial cells. Oncology Letters (2015) (2020 IF: 2.967)


Yoon SW, Kim DK, Kim KP, Park KS*. Rad51 regulates cell cycle progression by preserving G2/M transition in mouse embryonic stem cells. Stem Cells & Development. 23(22):2700-2711 (2014) (2020 IF: 3.272)


Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H, Lee HJ, Yoon TJ. Ultrasound-mediated gene and drug delivery using a microbubble-liposome particle system. Theranostics. 4(11):1133-1144 (2014)

(2020 IF: 11.556)


Heo SH, Cha Y, Park KS* Hyrooxyurea induces a hypersensitive apoptotic response in mouse embryonic stem cells through p38-dependent acetylation of p53. Stem Cells & Development. 23(20):2435-2442 (2014) (2020 IF: 3.272)


Kim DK, Cha Y, Ahn HJ, Kim G, Park KS*. Lefty1 and Lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells. Stem Cells & Development. 23(5):457-466 (2014) (2020 IF: 3.272)


Cha Y, Heo SH, Ahn HJ, Yang SK, Song J, Suh W, Park KS*. Tcea3 regulates the vascular differentiation potential of mouse embryonic stem cells. Gene Expression. 16(1):25-30 (2013) (2020 IF: 5.057)


Ahn HJ, Kim G, Park KS*. Ell3 stimulates proliferation, drug resistance, and cancer stem cell properties of breast cancer cells via a MEK/ERK-dependent signaling pathway. Biochem Biophys Res Commun 437(4):557-564 (2013) (2020 IF: 3.575)


Moon SH, Kim DK, Cha Y, Jeon I, Song J, Park KS*. PI3K and Stat3 signaling regulated by PETN control cancer stem cell population, proliferation and senescence in the glioblastoma cell line. International Journal of Oncology. 42(3):921-928 (2013) (2020 IF: 5.65)


Park KS*, Cha Y, Kim CH, Ahn HJ, Kim D, Ko S, Kim KH, Chang MY, Ko JH, Noh YS, Han YM, Kim J, Song J, Kim JY, Tesar PJ, Lanza R, Lee KA, Kim KS*. Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embyronic stem cells, via the Lefty1-Nodal-Smad2 pathway. Stem Cells. 31(2):282-292 (2013) (2020 IF: 6.022)


Cha Y, Kim DK, Hyun J, Kim SJ, Park KS*. Tcea3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells. Cellular Signaling. 25(5):1245-1251 (2013) (2020 IF: 4.315)


Jung JE, Moon SH, Kim DK, Choi C, Song J, Park KS*. Sprouty1 regulates neural and endothelial differentiation of mouse embryonic stem cells. Stem Cell & Development. 21(4):554-561 (2012) (2020 IF: 3.272)


Ahn HJ, Cha Y, Moon SH, Jung JE, Park KS*. Ell3 enhances differentiation of mouse embryonic stem cells by regulating epithelial-mesenchymal transition and apoptosis. PLoS ONE. 7(6):e40293 (2012) (2020 IF: 3.240)


Choi EH, Park JS, Park K, Park KS, Kim BS, Han IB, Shin DA, Lee SH. Effect of nucleus pulporous cells having different phenotype on chondrogenic differentiation of adipose-drived stromal cells in a co-culture system using porous membrane. Tissue Engineering (2011) (2020 IF: 3.845)


Cha Y, Park KS*. Shp-2 mediated Zap70 signaling in control of ERK1/2 and LIF receptor expression in mouse embryonic stem cells. FEBS Letters. 584:4241-4246 (2010) (2020 IF: 4.124)


Cha Y, Moon BH, Lee MO, Ahn HJ, Lee HJ, Lee KA, Fornace AJ, Kim KS, Cha HJ*, Park KS*. Zap70 functions to maintain stemness of embryonic stem cells by negatively regulating Jak1/Stat3 signaling. STEM CELLS. 28(9):1476-1486 (2010) (2020 IF: 6.022)


Lee HS, Kim YY, Kim kH, Moon JS, Park KS, Kim KS, Lee KA. Obox4 critically regulates cAMP-dependent meiotic arrest and MI-MII transition in oocytes. FASEB Journal. 24(7):2314-2324 (2010) (2020 IF: 5.191)


Chang MY, Kim D, Kim CH, Kang HC, Yang E, Moon J, Ko SH, Park J, Park KS*, Lee KA, Hwang DY, Chung Y, Lanza R, Kim KS. Direct reprogramming of rat neural precursor cells and fibroblasts into pluripotent stem cells. PLos One. 5(3):e9838 (2010) (2020 IF: 2.74)


Kim HM, Ahn HJ, Lee HS, Lee KA, Lee SM, Kim HH, Kim KS, Park KS*. Obox4 regulates the expression of histone family genes and promotes differentiation of mouse embryonic stem cells. FEBS Letters. 584:605-611 (2010) (2020 IF: 4.124)


Cha Y, Sung MK, Jung KW, Kim HH, Lee SM, Park KS* Epigenetic deregulation of the human Oct4 promoter in mouse cells. Dev Genes Evol. 218(10):561-6 (2008) (2020 IF: 0.9)


Park KS* & Kim JS. Engineering of GAL1Promoter-driven Expression System with Artificial Transcription Factors. Biochem. Bipphys. Res. Comm. 351(2):412-417 (2006) (2020 IF: 3.575)


Park KS., Jang YS., Lee H & Kim JS*. Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in E. coli. J. Bacteriology. 187, 5496-5499. (2005) (2020 IF: 3.219)


Park KS., Seol W., Yang HY., Lee SI., Kim SK., Kwon RJ., Kim EJ., Roh YH., Seong BL & Kim JS*. Identification and Use of Zinc Finger Transcription Factors That Increase Production of Recombinant Proteins in Yeast and Mammalian Cells. Biotechnology Progress .21. 664-670 (2005) (2020 IF: 2.455)


Park KS, Lee DK, Lee H, Lee Y, Jang YS, Kim YH, Yang HY, Lee SI, Seol W, Kim JS*. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nat. Biotechnol. 21, 1208-1214 (2003) (2020 IF: 54.908)


Bae KH, Kwon YD, Shin HC, Hwang MS, Ryu EH, Park KS, Yang HY, Lee DK, Lee Y, Park J, Kwon HS, Kim HW, Yeh BI, Lee HW, Sohn SH, Yoon J, Seol W, Kim JS*. Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat. Biotechnol. 21, 275–280 (2003) (2020 IF: 54.908)


Kim KS, Park KS*. XRP44X enhances the cytotoxic activity of natural killer cells by activating the c-Jun N-terminal kinase signaling pathway. Dev. Reprod (2020)


Lee JY, Oh N, Park KS*. Ell3 modulates the wound healing activity of conditioned medium of adipose-derived stem cells. Dev. Reprod (2017)


Lee JY, Kim DK, Ko JJ, Kim KP, Park KS*. Rad51 regulates reprogramming efficiency through DNA repair pathway. Dev. Reprod. 20(2):163-169 (2016)


Lee JY, Park S, Kim KS, Ko JJ, Lee S, Kim KP, Park KS*. Novel function of Sprouty4 as a regulator of stemness and differentiation of embryonic stem cells. Dev. Reprod. 20(2):171-177 (2016)


Park KS* TGF-β family signaling in embryonic stem cells. Int. J. Stem Cells. 4(1):18-23 (2011)


Jung JE, Park KS* The effect of Sprouty1 expression on the growth of mouse embryonic stem cells. Tissue Engineering and Regenerative Medicine. 7(5):623-630 (2010)


Kim DK, Cha Y, Ahn HJ, Park KS* Obox6 regulates phosphorylation of Stat3 in the mouse embryonic stem cells. Tissue Engineering and Regenerative Medicine. 7(4):460-465 (2010)


Kim HM, Kim HH, Lee SM, Suh WH, Park KS* The effect of passage number of cell culture on the characteristics of mouse embryonic stem cells. Tissue Engineering and Regenerative Medicine. 7(1):76-81 (2010)


Shin GH, Park KS, Chung KH, Lee TH 혈관내피성장인자에 의한 혈관에서 Interleukin-8 발현. 대한 혈액학회지 44(4):199-204 (2009)


Cha Y, Kwon SJ, Seol W, Park KS*. Estrogen Receptor-alpha Mediates the Effects of Estradiol on Telomerase Activity in Human Mesenchymal Stem Cells. Mol Cells. 26;454-458 (2008)


박경순. 유도만능세포의 최근 연구동향과 전망. Tissue Engineering and Regenerative Medicine. 5(3): 413-419 (2008)


Park KS., Lee H & Kim JS*. Enhacing the solubility of recombinant proteins in Escherichia coli with an artificial transcription factor library. J. Microbiol. Biotechnol. 16(2):299-302. (2006)

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